arXiv:2609.35882v1 Announce Type: new Abstract: Genome foundation models are most useful where sequences are generated, yet the largest models need datacenter accelerators and a place to send private DNA. We ask whether a 15-billion-parameter genome mixture-of-experts (MoE) model can instead run on volunteers' web browsers, with the experts spread across many untrusted devices, without changing its predictions and without revealing the sequence to any single device.

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